During exploration, hippocampal place cells activate one after the other forming sequences that represent the ongoing trajectory at the behavioral timescale. During subsequent slow wave sleep, the same sequences are endogenously replayed at a highly accelerated pace, contributing to memory consolidation. How is this sequential organization maintained across two different time scales, expressed at disjoint moments in time and during different brain states? We show that this requires faster sequences at the theta (~150 ms) time scale, nested within the slow, behavioral time scale sequences.
Our latest article was very favorably reviewed on F1000.
An interview by Yseult Berger for Universcience.tv about the hippocampo-cortical dialogue during sleep for memory consolidation.
À la une de l’émission « La Tête au carré », une interview de Mathieu Vidard et Axel Villard-Faure sur notre article du 16/05 dans Nature Neuroscience.
The CNRS and Inserm have issued press releases about our latest findings: